Cancer trials can lack clear information on biopsies
Michael Alcorn and Duncan Speakman by noii's
License (according to Flickr): Attribution-ShareAlike License
License (according to Flickr): Attribution-ShareAlike License
People participating in cancer drug trials aren't always given the most straightforward explanation of possible risks and benefits from invasive procedures that may be involved, according to a new study. Biopsies of tumor tissue can help researchers figure out how well a test drug is working - but the invasive, sometimes painful procedures are typically of little benefit to study participants themselves. The new findings show more than five percent of biopsies in such trials may result in complications, but that informed consent documents spend less time explaining those risks than they do for simple blood draws, which are much less invasive. "Most of these procedures don't have any therapeutic value for patients, they are burdensome, they're painful and they carry risk," said Jonathan Kimmelman, from the Biomedical Ethics Unit at McGill University in Montreal, Canada.
Keywords:
biopsies informed consent drug tumor Reuters Health MD Anderson Cancer Center cancer cancer drug procedure documents risks Biomedical Ethics McGill University painful biopsy scientific literature lung findings experimental Thirty-nine adequate five percent leaks bleeding honest volunteering alternatives therapeutic Oncology submit explanation Montreal institution research Houston fashion surgery problems therapy Michael Texas CanadaPeople:
Jonathan Kimmelman
Overall Sentiment: 0.162999
Relevance: 0.721229
| Sentiment | Quote |
|---|---|
| -0.138023 | "Most of these procedures don't have any therapeutic value for patients, they are burdensome, they're painful and they carry risk," said Jonathan Kimmelman, ... |
| 0.0145824 | "The only reason (patients) should submit to them is to contribute to science in some way," and not with the hope the biopsies will help them get better, he said. |
| -0.074817 | "The informed consent documents that are used are not always as clear as they could be," Kimmelman said. ... |
| 0.174708 | "I think a lot of patients understandably think that when they're volunteering for these studies they're giving tissue for what is cutting-edge science, and sometimes that's true, but not always," Kimmelman said. ... |
| Sentiment Stats: |
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Dr. Michael Overman
Overall Sentiment: 0.218583
Relevance: 0.700377
| Sentiment | Quote |
|---|---|
| 0.106984 | "I think giving biopsies is a good thing. I think you learn from it, but you need to do it in an honest fashion," Overman told ... |
| 0.0429942 | "This is where we should say (to patients), ‘This is an experimental therapy, an experimental biopsy, and you don't have to do it,'" Overman said. ... |
| Sentiment Stats: |
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Additional Info:
Company: Reuters
Overall Sentiment: 0.602188
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Organization: Anderson Cancer Center
Overall Sentiment: -0.281799
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Organization: University of Texas
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Organization: McGill University
Overall Sentiment: -0.0298234
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Disambiguation: Location | CollegeUniversity | UniversityReferences:
Country: Canada
Overall Sentiment: 0
Relevance: 0.321439
Disambiguation: Location | GovernmentalJurisdiction | Kingdom | AwardDiscipline | FilmScreeningVenueReferences:
City: Montreal
Overall Sentiment: -0.0135335
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City: Houston
Overall Sentiment: -0.780742
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PrintMedia: Journal of Clinical Oncology
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- health
- Houston
- liver
- Oncology
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- Texas
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People participating in cancer drug trials aren't always given the most straightforward explanation of possible risks and benefits from invasive procedures that may be involved, according to a new study
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Cancer trials can lack clear information on biopsies
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