Mad cow disease may hold clues to other neurological disorders
The rare bovine disorder, which infects cattle, and the human form, called Variant Creutzfeldt-Jakob disease, both fall into a category of so-called prion diseases, caused by aberrant proteins that spread aggressively from cell to cell. While the human variant of mad-cow disease isn't normally lumped together with Alzheimer's, Parkinson's or Lou Gehrig's disease, which affect millions of mostly older people world-wide, the conditions share the ability to spread and wreak havoc through the body. And although there isn't evidence that these more common neurological disorders are transmissible to people, researchers are finding that each condition is associated with a similar deformation in the structure of particular proteins needed for normal healthy functioning. Dozens of diseases are believed to be linked to deformed proteins, including Type 2 diabetes, cataracts and a type of emphysema.
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Neil R. Cashman
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| -0.0103135 | "Arrest it and we can potentially stop the disease," says Neil R. Cashman, ... |
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PrintMedia: The Wall Street Journal
Overall Sentiment: 0
Relevance: 0.345096
HealthCondition: Parkinson's disease
Overall Sentiment: -0.0356279
Relevance: 0.839522
HealthCondition: Creutzfeldt-Jakob disease
Overall Sentiment: -0.553561
Relevance: 0.64216
HealthCondition: Alzheimer
Overall Sentiment: 0.0118531
Relevance: 0.50212
HealthCondition: amyotrophic lateral sclerosis
Overall Sentiment: 0
Relevance: 0.400715
HealthCondition: Type 2 diabetes
Overall Sentiment: -0.191238
Relevance: 0.388675
HealthCondition: dementia
Overall Sentiment: -0.338205
Relevance: 0.387119
Organization: Center for Neurodegenerative Disease Research
Overall Sentiment: 0
Relevance: 0.552937
Organization: Brain Research Centre
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Relevance: 0.350782
Organization: University of Pennsylvania
Overall Sentiment: -0.25635
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Organization: University of British Columbia
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Relevance: 0.323235
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- alzheimers
- cataracts
- creutzfeldt-jakob disease
- dementia
- lou gehrigs
- parkinsons disease
- the animals
- Type 2 diabetes
- University of Pennsylvania
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